KAI715 | CAS#unknown | Antimalarial agent

MedKoo Cat#: 463908 | Name: KAI715

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KAI715 is a antimalarial agent.

Chemical Structure

KAI715

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 463908

Name: KAI715

CAS#: unknown

Chemical Formula: C22H14F3N5O

Exact Mass: 421.1150

Molecular Weight: 421.38

Elemental Analysis: C, 62.71; H, 3.35; F, 13.53; N, 16.62; O, 3.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

KAI715; KAI 715; KAI-715;

IUPAC/Chemical Name

N-(4-cyanophenyl)-N-methyl-3-(4-(trifluoromethyl)phenyl)imidazo[1,2-b]pyridazine-6-carboxamide

InChi Key

PTAYSTWYUWWEED-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H14F3N5O/c1-29(17-8-2-14(12-26)3-9-17)21(31)18-10-11-20-27-13-19(30(20)28-18)15-4-6-16(7-5-15)22(23,24)25/h2-11,13H,1H3

SMILES Code

CN(C(C1=NN2C(C=C1)=NC=C2C3=CC=C(C(F)(F)F)C=C3)=O)C4=CC=C(C#N)C=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 421.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ren JX, Gao NN, Cao XS, Hu QA, Xie Y. Homology modeling and virtual screening for inhibitors of lipid kinase PI(4)K from Plasmodium. Biomed Pharmacother. 2016 Oct;83:798-808. doi: 10.1016/j.biopha.2016.07.048. Epub 2016 Aug 2. PMID: 27490781.