MedKoo Cat#: 575821 | Name: Gatifloxacin mesylate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Gatifloxacin mesylate is a bacterial DNA gyrase inhibitor used to treat tuberculosis and pneumonia.

Chemical Structure

Gatifloxacin mesylate
Gatifloxacin mesylate
CAS#316819-28-0 (mesyalate)

Theoretical Analysis

MedKoo Cat#: 575821

Name: Gatifloxacin mesylate

CAS#: 316819-28-0 (mesyalate)

Chemical Formula: C20H26FN3O7S

Exact Mass: 0.0000

Molecular Weight: 471.50

Elemental Analysis: C, 50.95; H, 5.56; F, 4.03; N, 8.91; O, 23.75; S, 6.80

Price and Availability

Size Price Availability Quantity
500mg USD 450.00 2 Weeks
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Synonym
Gatifloxacin mesylate; Gatifloxacin (mesylate); Gatifloxacin mesilate; AM1155; AM 1155; AM-1155; BMS 206584-01; BMS206584-01; BMS-206584-01; PD 135432; PD135432; PD-135432
IUPAC/Chemical Name
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate
InChi Key
PMMNVFFMFJMFDB-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H22FN3O4.CH4O3S/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26;1-5(2,3)4/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26);1H3,(H,2,3,4)
SMILES Code
COc1c(N2CCNC(C)C2)c(F)cc3C(=O)C(=CN(C4CC4)c13)C(=O)O.CS(=O)(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 471.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Khurana G, Arora S, Pawar PK. Ocular insert for sustained delivery of gatifloxacin sesquihydrate: Preparation and evaluations. Int J Pharm Investig. 2012 Apr;2(2):70-7. doi: 10.4103/2230-973X.100040. PubMed PMID: 23119235; PubMed Central PMCID: PMC3482768. 2: Gilhotra RM, Mishra DN. Alginate-chitosan film for ocular drug delivery: effect of surface cross-linking on film properties and characterization. Pharmazie. 2008 Aug;63(8):576-9. PubMed PMID: 18771005. 3: Wells MY, Krinke GJ. Cerebral vacuolation induced in rats by the administration of LUP-3FDC, an anti-tuberculosis cocktail. Exp Toxicol Pathol. 2008 Apr;59(6):365-72. doi: 10.1016/j.etp.2007.11.006. Epub 2008 Jan 25. PubMed PMID: 18222073.