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MedKoo Cat#: 412923 | Name: Cinpropazide maleate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cinpropazide maleate is a potent vasodilator exerting principal action on intramyocardial circulation increasing the blood flow of the coronary vessels & of the endocardic microcirculation.

Chemical Structure

Cinpropazide maleate
Cinpropazide maleate
CAS#26328-00-7 (maleate)

Theoretical Analysis

MedKoo Cat#: 412923

Name: Cinpropazide maleate

CAS#: 26328-00-7 (maleate)

Chemical Formula: C25H35N3O9

Exact Mass: 521.2373

Molecular Weight: 521.57

Elemental Analysis: C, 57.57; H, 6.76; N, 8.06; O, 27.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
23887-47-0 (free base) 26328-00-7 (maleate)
Synonym
Cinpropazide maleate; MD68111; MD-68111; MD 68111
IUPAC/Chemical Name
1-Piperazineacetamide, N-(1-methylethyl)-4-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-, (Z)-2-butenedioate (1:1)
InChi Key
WOSAGTMAYYLCTD-GVTSEVKNSA-N
InChi Code
InChI=1S/C21H31N3O5.C4H4O4/c1-15(2)22-19(25)14-23-8-10-24(11-9-23)20(26)7-6-16-12-17(27-3)21(29-5)18(13-16)28-4;5-3(6)1-2-4(7)8/h6-7,12-13,15H,8-11,14H2,1-5H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b7-6+;2-1-
SMILES Code
O=C(NC(C)C)CN1CCN(C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O)CC1.O=C(O)/C=C\C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 521.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sakai K, Haga N, Fujisawa Y, Abiko Y. Effect of cinpropazide on ischemic myocardial acidosis in dogs. Arch Int Pharmacodyn Ther. 1985 Sep;277(1):83-91. PMID: 4062435. 2: Nonaka K, Ueno A. Effects of intravenously and orally administered cinpropazide on the coronary circulation in unanesthetized and unrestrained dogs. Arzneimittelforschung. 1985;35(10):1499-502. PMID: 4074404. 3: Oliver C, Rabiant J. Métabolisme du cinpropazide chez l'homme. Excrétion urinaire et taux plasmatique [The metabolism of cinpropazide in man. Urinary excretion and plasma concentration]. Ann Pharm Fr. 1975 Jun-Jul;33(6-7):301-12. French. PMID: 1220600. 4: Rabiant J, Oliver C, Ancher JF, Sergant M, Bouvet P. Métabolites urinaires du maléate de N-isopropyl ((triméthoxy-3,4,5 cinnamoyl)-4 pipérazinyl-1)-2 acétamide (cinpropazide) chez le Chien [Urinary metabolites of N-isopropyl 2-(4-(3,4,5-trimethoxycinnamoyl)-1-piperazinyl)acetamide (cinpropazide) in the dog]. Ann Pharm Fr. 1974 Mar-Apr;32(3-4):183-92. French. PMID: 4433119.