MedKoo Cat#: 463736 | Name: KMN-010034

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KMN-010034 is a novel Potent Hematopoietic Prostaglandin D2 Synthase (H-PGDS) Inhibitor.

Chemical Structure

KMN-010034
KMN-010034
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 463736

Name: KMN-010034

CAS#: unknown

Chemical Formula: C24H20N6O2

Exact Mass: 424.1648

Molecular Weight: 424.46

Elemental Analysis: C, 67.91; H, 4.75; N, 19.80; O, 7.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
KMN-010034; KMN010034; KMN 010034;
IUPAC/Chemical Name
2-(3-(3-(5-(2-phenylpyrimidin-5-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazol-5-yl)propan-2-ol
InChi Key
FRQTUESDJOPFQT-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H20N6O2/c1-24(2,31)23-29-22(30-32-23)17-10-6-9-16(11-17)21-27-14-19(28-21)18-12-25-20(26-13-18)15-7-4-3-5-8-15/h3-14,31H,1-2H3,(H,27,28)
SMILES Code
CC(O)(C1=NC(C2=CC=CC(C3=NC=C(C4=CN=C(C5=CC=CC=C5)N=C4)N3)=C2)=NO1)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 424.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Olson KL, Holt MC, Ciske FL, Kramer JB, Heiple PE, Collins ML, Johnson CM, Ho CS, Ines Morano M, Barrett SD. Novel Amide and Imidazole Compounds as Potent Hematopoietic Prostaglandin D2 Synthase Inhibitors. Bioorg Med Chem Lett. 2020 Dec 28:127759. doi: 10.1016/j.bmcl.2020.127759. Epub ahead of print. PMID: 33383152.