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MedKoo Cat#: 412741 | Name: Prisotinol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.

Chemical Structure

Prisotinol
CAS#76906-79-1 (free base)

Theoretical Analysis

MedKoo Cat#: 412741

Name: Prisotinol

CAS#: 76906-79-1 (free base)

Chemical Formula: C11H18N2O

Exact Mass: 194.1419

Molecular Weight: 194.28

Elemental Analysis: C, 68.01; H, 9.34; N, 14.42; O, 8.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
76906-72-4 (2HCl) 76906-79-1 (free base)
Synonym
Prisotinol; CGS5649B; CGS 5649B; CGS-5649B
IUPAC/Chemical Name
3-Pyridinol, 6-(2-((1-methylethyl)amino)propyl)-
InChi Key
WQRPBKUCJBWQRT-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H18N2O/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10/h4-5,7-9,13-14H,6H2,1-3H3
SMILES Code
OC1=CC=C(CC(NC(C)C)C)N=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 194.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Molloy DW, Guyatt GH, Standish T, Willan A, McIlroy W, D'Souza J, Brown G, Mondadori C. Effect of a new nootropic agent, CGS 5649B, on cognition, function, and behavior in dementia. J Gen Intern Med. 1993 Aug;8(8):444-7. doi: 10.1007/BF02599624. PMID: 8410411. 2: Mondadori C, Ducret T, Borkowski J. How long does 'memory consolidation' take? New compounds can improve retention performance, even if administered up to 24 hours after the learning experience. Brain Res. 1991 Jul 26;555(1):107-11. doi: 10.1016/0006-8993(91)90866-t. PMID: 1933323. 3: Nilsson E, Schneider T, Hoffmann E, Schmidt EK. Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man. Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:201-4. PMID: 1820879.