KM-5-25 is a novel inhibitor of the BfrB-Bfd complex, binding BfrB in the P. aeruginosa cytosol, blocking the BfrB-Bfd interaction and inhibiting iron mobilization from BfrB, resulting in cytosolic iron limitation that is manifested in a pyoverdine hyperproduction phenotype.
MedKoo Cat#: 463620
Name: KM-5-25
CAS#: unknown
Chemical Formula: C15H11ClN2O3
Exact Mass: 302.0458
Molecular Weight: 302.71
Elemental Analysis: C, 59.52; H, 3.66; Cl, 11.71; N, 9.25; O, 15.86
The following data is based on the product molecular weight 302.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
