Romergoline | CAS# 107052-56-2 | Biochemical

MedKoo Cat#: 575341 | Name: Romergoline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Romergoline is a putative dopamine D1 agonist and D2 antagonist.

Chemical Structure

Romergoline

CAS#107052-56-2

Theoretical Analysis

MedKoo Cat#: 575341

Name: Romergoline

CAS#: 107052-56-2

Chemical Formula: C20H22N4O2

Exact Mass: 350.1743

Molecular Weight: 350.42

Elemental Analysis: C, 68.55; H, 6.33; N, 15.99; O, 9.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Romergoline; FCE23884; FCE 23884; FCE-23884

IUPAC/Chemical Name

2,6-Piperazinedione, 4-(((8beta)-9,10-didehydro-6-methylergolin-8-yl)methyl)-

InChi Key

RJCXNCSJGRUWRW-SJKOYZFVSA-N

InChi Code

InChI=1S/C20H22N4O2/c1-23-8-12(9-24-10-18(25)22-19(26)11-24)5-15-14-3-2-4-16-20(14)13(7-21-16)6-17(15)23/h2-5,7,12,17,21H,6,8-11H2,1H3,(H,22,25,26)/t12-,17-/m1/s1

SMILES Code

CN1C[C@H](CN2CC(=O)NC(=O)C2)C=C3[C@H]1Cc4c[nH]c5cccc3c45

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 350.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Metman LV, Blanchet PJ, de Jong D, Mouradian MM, Chase TN. Effect of the putative dopamine D1 agonist and D2 antagonist FCE 23884 on Parkinson's disease. Mov Disord. 1996 May;11(3):257-60. doi: 10.1002/mds.870110307. PMID: 8723141. 2. Buonamici M, Cervini MA, Maj R, Mantegani S, Rossi AC. A new dopamine agonist in dopamine deprived systems: FCE 23884. Neurochem Int. 1992 Mar;20 Suppl:179S-183S. doi: 10.1016/0197-0186(92)90235-j. PMID: 1365422.