HOE-768159 | CAS# 79173-80-1 | Biochemical

MedKoo Cat#: 576336 | Name: HOE-768159

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HOE-768159 is a biochemical that reversibly arrests the T-lymphocyte cell cycle near the G1/S boundary.

Chemical Structure

HOE-768159

CAS#79173-80-1

Theoretical Analysis

MedKoo Cat#: 576336

Name: HOE-768159

CAS#: 79173-80-1

Chemical Formula: C11H11NO3S

Exact Mass: 237.0460

Molecular Weight: 237.27

Elemental Analysis: C, 55.68; H, 4.67; N, 5.90; O, 20.23; S, 13.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

HOE768159; HOE 768159; HOE-768159

IUPAC/Chemical Name

4-Thiazolecarboxylic acid, 4,5-dihydro-2-(2-hydroxy-5-methylphenyl)-

InChi Key

OEVXWWFLUUMMHL-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H11NO3S/c1-6-2-3-9(13)7(4-6)10-12-8(5-16-10)11(14)15/h2-4,8,13H,5H2,1H3,(H,14,15)

SMILES Code

Cc1ccc(O)c(c1)C2=NC(CS2)C(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 237.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Hoffman BD, Hanauske-Abel HM, Flint A, Lalande M. A new class of reversible cell cycle inhibitors. Cytometry. 1991;12(1):26-32. doi: 10.1002/cyto.990120105. PMID: 1900227. 2. Kim YH, Buchholz MA, Chrest FJ, Nordin AA. Up-regulation of c-myc induces the gene expression of the murine homologues of p34cdc2 and cyclin-dependent kinase-2 in T lymphocytes. J Immunol. 1994 May 1;152(9):4328-35. PMID: 8157956. 3. Lalande M, Hanauske-Abel HM. A new compound which reversibly arrests T lymphocyte cell cycle near the G1/S boundary. Exp Cell Res. 1990 May;188(1):117-21. doi: 10.1016/0014-4827(90)90285-i. PMID: 2328769.