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MedKoo Cat#: 412584 | Name: Oxaflozane (free base)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oxaflozane is a non-tricyclic antidepressant with serotoninergic action. In animals, oxaflozane has anti-cataleptic and anti-aggressive action with weak potentiation of stereotypes provoked by amphetamine. Oxaflozane was developed by Solvay Pharma and marketed in France under tradename Conflictan. The drug was discontinued in 2004.

Chemical Structure

Oxaflozane (free base)
Oxaflozane (free base)
CAS#26629-87-8 (free base)

Theoretical Analysis

MedKoo Cat#: 412584

Name: Oxaflozane (free base)

CAS#: 26629-87-8 (free base)

Chemical Formula: C14H18F3NO

Exact Mass: 273.1340

Molecular Weight: 273.29

Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 61.53; H, 6.64; F, 20.85; N, 5.13; O, 5.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
26629-87-8 (free base) 26629-86-7 (HCl)
Synonym
Oxaflozane; EINECS 247-855-8; Oxaflozanum
IUPAC/Chemical Name
4-(1-Methylethyl)-2-(3-(trifluoromethyl)phenyl)morpholine
InChi Key
FVYUQFQCEOZYHZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H18F3NO/c1-10(2)18-6-7-19-13(9-18)11-4-3-5-12(8-11)14(15,16)17/h3-5,8,10,13H,6-7,9H2,1-2H3
SMILES Code
FC(C1=CC(C2CN(C(C)C)CCO2)=CC=C1)(F)F
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 273.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Constantin M, Pognat JF. Comparative study of oxaflozane urinary metabolism in man, the dog and the rat. Identification of the principal metabolites. Arzneimittelforschung. 1979;29(1):109-14. PMID: 582104. 2: Hache J, Duchene-Marullaz P, Streichenberger G. Profil pharmacologique d'un nouvel antidépresseur non tricyclique: l'oxaflozane (1.766 Cerm) [Pharmacological profile of a new non tricyclic antidepressant: oxaflozane (1,766 Cerm)]. Therapie. 1974 Jan-Feb;29(1):81-93. French. PMID: 4849381. 3: Rascol A, Maurel H, David J, Layani M. Premiers résultats cliniques d'un nouvel antidépresseur non tricyclique: "loxaflozane" (1766 cerm) [Preliminary clinical results of a new non tricyclic antidepressive drug: oxaflozane]. Therapie. 1974 Jan-Feb;29(1):95-9. French. PMID: 4603757. 4: Dutertre JP, Barbier P, Suc AL, Jonville AP, Autret E. Oxaflozane overdose in a child. J Toxicol Clin Toxicol. 1992;30(1):123-6. doi: 10.3109/15563659208994452. PMID: 1542141. 5: Cosnier D, Grimal J, Rispat G, Streichenberger G. Propriétés cardiovasculaires de ĺoxaflozane (1,766 CERM) nouvel antiddpresseur non tricyclique [Cardiovascular properties of oxaflozane (1,766 CERM), a new non- tricyclic antidepressive]. Therapie. 1975 Jul-Aug;(4):539-54. French. PMID: 1209529. 6: Denber HC. Trials with drugs outside the United States. Dis Nerv Syst. 1974 Jul;35(7 Pt. 2):8-9. PMID: 17894094.