CAD-31, also known as CAD-031, is a novel brain penetrant, J147-derivative and an Alzheimer's disease (AD) drug candidate. CAD-31 has potent neuroprotective properties in six distinct nerve cell assays that mimic toxicities observed in the old brain. CAD-31 is brain-penetrant and likely safe. CAD-31 had major effects on synapse formation and AD energy metabolic pathways. CAD-31 were favorable in the context of preventing some of the toxic events in old age-associated neurodegenerative diseases.
MedKoo Cat#: 555892
Name: CAD-31
CAS#: 2071209-49-7
Chemical Formula: C18H14F6N2O2
Exact Mass: 404.0959
Molecular Weight: 404.31
Elemental Analysis: C, 53.47; H, 3.49; F, 28.19; N, 6.93; O, 7.91
The following data is based on the product molecular weight 404.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
