MedKoo Cat#: 575175 | Name: Azapetine free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azapetine is a vasodilator that has been investigated for its effects on peripheral arterial disease. It exhibits bioactivity by interacting with adrenergic receptors. Specifically, azapetine has an IC₅₀ value of 5.89 μM for alpha-2 adrenergic receptors and 6.69 μM for alpha-1 adrenergic receptors, indicating its inhibitory potency at these sites. Azapetine functions as an adrenergic receptor antagonist, primarily blocking alpha-1 and alpha-2 adrenergic receptors. By inhibiting these receptors, it reduces vasoconstriction, leading to vasodilation and improved blood flow. This mechanism contributes to its therapeutic potential in conditions involving vascular insufficiency.

Chemical Structure

Azapetine free base
Azapetine free base
CAS#146-36-1 (free base)

Theoretical Analysis

MedKoo Cat#: 575175

Name: Azapetine free base

CAS#: 146-36-1 (free base)

Chemical Formula: C17H17N

Exact Mass: 235.1361

Molecular Weight: 235.33

Elemental Analysis: C, 86.77; H, 7.28; N, 5.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Azapetine; Ilidar Base
IUPAC/Chemical Name
6-Allyl-6,7-dihydro-5H-dibenz(c,e)azepine
InChi Key
NYGHGTMKALXFIA-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H17N/c1-2-11-18-12-14-7-3-5-9-16(14)17-10-6-4-8-15(17)13-18/h2-10H,1,11-13H2
SMILES Code
C=CCN1Cc2ccccc2c3ccccc3C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 235.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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