Ormeloxifene, also known as centchroman, is one of the selective estrogen receptor modulators, or SERMs, a class of medication which acts on the estrogen receptor. Ormeloxifene is a selective estrogen receptor modulator (SERM). In some parts of the body, its action is estrogenic (e.g., bones), in other parts of the body, its action is antiestrogenic (e.g., uterus, breasts). It causes an asynchrony in the menstrual cycle between ovulation and the development of the uterine lining, although its exact mode of action is not well defined. In clinical trials, it caused ovulation to occur later than it normally would in some women, ] but did not affect ovulation in the majority of women, while causing the lining of the uterus to build more slowly.
MedKoo Cat#: 412561
Name: Ormeloxifene HCl
CAS#: 51023-56-4 (HCl)
Chemical Formula: C30H36ClNO3
Exact Mass: 0.0000
Molecular Weight: 494.07
Elemental Analysis: C, 72.93; H, 7.34; Cl, 7.18; N, 2.84; O, 9.71
The following data is based on the product molecular weight 494.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
