MedKoo Cat#: 412521 | Name: Cefoxazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cefoxazole is an antibiotic used in treatment of bovine mastitis.

Chemical Structure

Cefoxazole
CAS#36920-48-6

Theoretical Analysis

MedKoo Cat#: 412521

Name: Cefoxazole

CAS#: 36920-48-6

Chemical Formula: C21H18ClN3O7S

Exact Mass: 491.0554

Molecular Weight: 491.89

Elemental Analysis: C, 51.28; H, 3.69; Cl, 7.21; N, 8.54; O, 22.77; S, 6.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Cefoxazole; Cefoxazolum; Cephoxazol; Glaxo 291/1; Cephoxazole
IUPAC/Chemical Name
(6R,7R)-7-(3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid acetate (ester)
InChi Key
OCLRGULJISNUQS-OXQOHEQNSA-N
InChi Code
InChI=1S/C21H18ClN3O7S/c1-9-14(15(24-32-9)12-5-3-4-6-13(12)22)18(27)23-16-19(28)25-17(21(29)30)11(7-31-10(2)26)8-33-20(16)25/h3-6,16,20H,7-8H2,1-2H3,(H,23,27)(H,29,30)/t16-,20-/m1/s1
SMILES Code
O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](NC(C3=C(C)ON=C3C4=CC=CC=C4Cl)=O)C1=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 491.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Harris AM, Davies AM, Marshall MJ, Evans JM, Hendy PG, Watson DJ. The treatment of clinical mastitis with cephoxazole and penicillin. Vet Rec. 1977 Jul 2;101(1):4-7. doi: 10.1136/vr.101.1.4. PMID: 888320. 2: Boulton MG, Ross GW. Resistance of cephoxazole-benzylpenicillin combinations to destruction by beta-lactamases associated with bovine mastitis. J Comp Pathol. 1977 Jan;87(1):145-33. doi: 10.1016/0021-9975(77)90090-1. PMID: 320234. 3: Ziv G. Availability and usage of new antibacterial drugs in Europe. J Am Vet Med Assoc. 1980 May 15;176(10 Spec No):1122-8. PMID: 7216885.