MedKoo Cat#: 598634 | Name: Leucasin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Leucasin is a triterpene saponin from Leucas nutans.

Chemical Structure

Leucasin
Leucasin
CAS#140231-39-6

Theoretical Analysis

MedKoo Cat#: 598634

Name: Leucasin

CAS#: 140231-39-6

Chemical Formula: C42H70O12

Exact Mass: 766.4867

Molecular Weight: 767.01

Elemental Analysis: C, 65.77; H, 9.20; O, 25.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Leucasin;
IUPAC/Chemical Name
(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-2-(((1R,3aR,5aR,5bR,7aR,11aR,13aR,13bR)-10-hydroxy-3a,5a,5b,8,8,11a-hexamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChi Key
HJPIQGMZMGIUBT-OIISAJIDSA-N
InChi Code
InChI=1S/C42H70O12/c1-20(2)21-11-13-39(5)15-16-41(7)22(28(21)39)9-10-27-40(6)17-23(45)35(38(3,4)26(40)12-14-42(27,41)8)54-37-34(32(49)30(47)25(19-44)52-37)53-36-33(50)31(48)29(46)24(18-43)51-36/h21-37,43-50H,1,9-19H2,2-8H3/t21-,22+,23?,24+,25+,26-,27?,28+,29+,30+,31-,32-,33+,34+,35?,36-,37-,39+,40-,41+,42+/m0/s1
SMILES Code
CC([C@@H]1CC[C@@]2(C)[C@H]1[C@H]3CCC4[C@](CC[C@@H]5[C@]4(C)CC(O)C(O[C@H]6[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)[C@@H](O)[C@H](O)[C@@H](CO)O6)C5(C)C)(C)[C@]3(C)CC2)=C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 767.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hasan M, Burdi DK, Ahmad VU. Leucasin, a triterpene saponin from Leucas nutans. Phytochemistry. 1991;30(12):4181-3. PubMed PMID: 1367878. 2: Sakthivel G, Dey A, Nongalleima Kh, Chavali M, Rimal Isaac RS, Singh NS, Deb L. In Vitro and In Vivo Evaluation of Polyherbal Formulation against Russell's Viper and Cobra Venom and Screening of Bioactive Components by Docking Studies. Evid Based Complement Alternat Med. 2013;2013:781216. doi: 10.1155/2013/781216. Epub 2013 Feb 28. PubMed PMID: 23533518; PubMed Central PMCID: PMC3600290.