JMX0510-2 is a Potent Human Adenovirus Inhibitor. JMX0510-2 showed improved anti-HAdV activity (IC50 = 0.27 μM), significantly decreased cytotoxicity (CC50 = 156.8 μM), and low in vivo toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide.
MedKoo Cat#: 463394
Name: JMX0510-2
CAS#: unknown
Chemical Formula: C19H20Cl2N2O2
Exact Mass: 378.0902
Molecular Weight: 379.28
Elemental Analysis: C, 60.17; H, 5.32; Cl, 18.69; N, 7.39; O, 8.44
The following data is based on the product molecular weight 379.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
