Echinuline | CAS#1859-87-6 | Diketopiperazine metabolite

MedKoo Cat#: 463381 | Name: Echinuline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Echinulin is a diketopiperazine metabolite found in fungi that, when administered to rabbits, at a dose of 10 mg/kg, leads to liver and lung damage. It has no activity at the δ, κ, or µ-opioid receptors or the cannabinoid CB1 and CB2 receptors.

Chemical Structure

Echinuline

CAS#1859-87-6

Theoretical Analysis

MedKoo Cat#: 463381

Name: Echinuline

CAS#: 1859-87-6

Chemical Formula: C29H39N3O2

Exact Mass: 461.3042

Molecular Weight: 461.65

Elemental Analysis: C, 75.45; H, 8.52; N, 9.10; O, 6.93

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Synonym

Echinuline; Echinulin;

IUPAC/Chemical Name

(3S,6S)-3-((5,7-bis(3-methylbut-2-en-1-yl)-2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl)methyl)-6-methylpiperazine-2,5-dione

InChi Key

DIKMWTRJIZQJMY-CYFREDJKSA-N

InChi Code

InChI=1S/C29H39N3O2/c1-9-29(7,8)26-23(16-24-28(34)30-19(6)27(33)31-24)22-15-20(12-10-17(2)3)14-21(25(22)32-26)13-11-18(4)5/h9-11,14-15,19,24,32H,1,12-13,16H2,2-8H3,(H,30,34)(H,31,33)/t19-,24-/m0/s1

SMILES Code

C[C@H](N1)C(N[C@@H](CC2=C(C(C)(C=C)C)NC3=C2C=C(C/C=C(C)\C)C=C3C/C=C(C)/C)C1=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 461.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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