Carvotroline (free base) | CAS# 107266-08-0 (free base) | antipsychotic

MedKoo Cat#: 412411 | Name: Carvotroline (free base)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carvotroline (free base) is a novel γ-carboline derivative with a preclinical profile suggestive of antipsychotic activity

Chemical Structure

Carvotroline (free base)

CAS#107266-08-0 (free base)

Theoretical Analysis

MedKoo Cat#: 412411

Name: Carvotroline (free base)

CAS#: 107266-08-0 (free base)

Chemical Formula: C18H18FN3

Exact Mass: 295.1485

Molecular Weight: 295.36

Elemental Analysis: C, 73.20; H, 6.14; F, 6.43; N, 14.23

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

107266-08-0 (free base) 136777-43-0 (HCl)

Synonym

Carvotroline (free base); UNII-1Q63WWP8G5

IUPAC/Chemical Name

8-fluoro-2-(2-(pyridin-4-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

InChi Key

PMXOASNGMJAYTN-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H18FN3/c19-14-1-2-17-15(11-14)16-12-22(10-6-18(16)21-17)9-5-13-3-7-20-8-4-13/h1-4,7-8,11,21H,5-6,9-10,12H2

SMILES Code

Fc(cc1)cc2c1[nH]c3c2CN(CCc4ccncc4)CC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 295.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Matheson GK, Knowles A, Gage D, Michel C, Guthrie D, Bauer C, Blackbourne J, Weinzapfel D. Modification of hypothalamic-pituitary-adrenocortical activity by serotonergic agents in the rat. Pharmacology. 1997 Aug;55(2):59-65. doi: 10.1159/000139513. PMID: 9323305.