Notum-IN-24 is a novel potent notum inhibitor (OPTS IC50 3.6nM; TCF-LEF EC50 220nM), showing good plasma exposure and reasonable CNS penetration.
MedKoo Cat#: 463334
Name: Notum-IN-24
CAS#: unknown
Chemical Formula: C14H13F3N4O3S
Exact Mass: 374.0660
Molecular Weight: 374.34
Elemental Analysis: C, 44.92; H, 3.50; F, 15.23; N, 14.97; O, 12.82; S, 8.56
The following data is based on the product molecular weight 374.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
