MedKoo Cat#: 574988 | Name: Arctigenin methyl ether

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Arctigenin methyl ether is a lignan found in certain plants of the Asteraceae, including the greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects in vitro. It is the aglycone of arctiin. The use of arctigenin has been shown to be effective in a mouse model of Japanese encephalitis.

Chemical Structure

Arctigenin methyl ether
CAS#25488-59-9 (methyl ether)

Theoretical Analysis

MedKoo Cat#: 574988

Name: Arctigenin methyl ether

CAS#: 25488-59-9 (methyl ether)

Chemical Formula: C22H26O6

Exact Mass: 386.1729

Molecular Weight: 386.44

Elemental Analysis: C, 68.38; H, 6.78; O, 24.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Arctigenin methyl ether
IUPAC/Chemical Name
2(3H)-Furanone, 3,4-bis((3,4-dimethoxyphenyl)methyl)dihydro-, (3R-trans)-
InChi Key
SNAOLIMFHAAIER-DLBZAZTESA-N
InChi Code
InChI=1S/C22H26O6/c1-24-18-7-5-14(11-20(18)26-3)9-16-13-28-22(23)17(16)10-15-6-8-19(25-2)21(12-15)27-4/h5-8,11-12,16-17H,9-10,13H2,1-4H3/t16-,17+/m0/s1
SMILES Code
COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(OC)c(OC)c3)cc1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 386.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shi X, Sun H, Zhou D, Xi H, Shan L. Arctigenin Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Rats. Inflammation. 2014 Jul 10. [Epub ahead of print] PubMed PMID: 25008149.