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MedKoo Cat#: 463330 | Name: SF-3-030

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SF-3-030 is a novel inhibitor of mutant-BRAF expressing melanoma cells by inducing oxidative stress, showing rapid changes in immediate early gene (IEG) levels including DEF motif containing ERK1/2 substrates in the Fos family.

Chemical Structure

SF-3-030
SF-3-030
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 463330

Name: SF-3-030

CAS#: unknown

Chemical Formula: C14H12O5S2

Exact Mass: 324.0126

Molecular Weight: 324.37

Elemental Analysis: C, 51.84; H, 3.73; O, 24.66; S, 19.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SF-3-030; SF3-030; SF 3-030; SF-3030; SF-3 030; SF 3 030; SF3030;
IUPAC/Chemical Name
1,1-dioxido-2,3-dihydrothiophen-3-yl naphthalene-2-sulfonate
InChi Key
UPNQDWDUYZHCMB-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H12O5S2/c15-20(16)8-7-13(10-20)19-21(17,18)14-6-5-11-3-1-2-4-12(11)9-14/h1-9,13H,10H2
SMILES Code
O=S(C1=CC=C2C=CC=CC2=C1)(OC(C=C3)CS3(=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 324.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Martinez R 3rd, Huang W, Samadani R, Mackowiak B, Centola G, Chen L, Conlon IL, Hom K, Kane MA, Fletcher S, Shapiro P. Mechanistic analysis of an ERK2-interacting compound that inhibits mutant-BRAF expressing melanoma cells by inducing oxidative stress. J Pharmacol Exp Ther. 2020 Oct 27:JPET- AR-2020-000266. doi: 10.1124/jpet.120.000266. Epub ahead of print. PMID: 33109619.