BAY1217224 is an orally bioavailable, selective, neutral, non-prodrug thrombin inhibitor with IC50 = 0.7 nM. BAY1217224 is highly selective and has excellent Caco-2 permeability, moderate clearance, and no CYP induction potential in hepatocytes. The compound has reached clinical trials which have confirmed oral bioavailability in healthy male volunteers.
MedKoo Cat#: 463326
Name: BAY1217224
CAS#: unknown
Chemical Formula: C24H27ClFN3O5
Exact Mass: 491.1623
Molecular Weight: 491.94
Elemental Analysis: C, 58.60; H, 5.53; Cl, 7.21; F, 3.86; N, 8.54; O, 16.26
The following data is based on the product molecular weight 491.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
