Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine. It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
MedKoo Cat#: 463306
Name: Desethyl Hydroxychloroquine-d4
CAS#: 1854126-47-8 (deuterated forms d1-d4)
Chemical Formula: C16H18D4ClN3O
Exact Mass: 311.1702
Molecular Weight: 311.85
Elemental Analysis: C, 61.63; H, 8.40; Cl, 11.37; N, 13.47; O, 5.13
The following data is based on the product molecular weight 311.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
