MedKoo Cat#: 574949 | Name: Zoledronate disodium hydrate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Zoledronate disodium hydrate is a bisphosphonate compound that inhibits osteoclast-mediated bone resorption and is widely used in bone metabolism and cancer research. It is highly water-soluble, forms metal ion complexes, and exhibits stability under normal conditions but requires moisture protection. Common applications include studying bone diseases, tumor-induced bone loss, and anti-inflammatory mechanisms.

Chemical Structure

Zoledronate disodium hydrate
Zoledronate disodium hydrate
CAS#165800-07-7 (disodium hydrate)

Theoretical Analysis

MedKoo Cat#: 574949

Name: Zoledronate disodium hydrate

CAS#: 165800-07-7 (disodium hydrate)

Chemical Formula: C5H16N2Na2O11P2

Exact Mass: 0.0000

Molecular Weight: 388.11

Elemental Analysis: C, 15.47; H, 4.16; N, 7.22; Na, 11.85; O, 45.34; P, 15.96

Price and Availability

Size Price Availability Quantity
1g USD 3,650.00 4-6 weeks
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Synonym
Zoledronic Acid Disodium Salt Tetrahydrate; Zoledronate Disodium, Zoledronate disodium hydrate; CGP-42446A; CGP 42446A; CGP42446A;
IUPAC/Chemical Name
Phosphonic acid, (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bis-, disodium salt, tetrahydrate
InChi Key
IEJZOPBVBXAOBH-UHFFFAOYSA-L
InChi Code
InChI=1S/C5H10N2O7P2.2Na.4H2O/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7;;;;;;/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14);;;4*1H2/q;2*+1;;;;/p-2
SMILES Code
OC(P([O-])([O-])=O)(P(O)(O)=O)CN1C=CN=C1.[H]O[H].[H]O[H].[H]O[H].[H]O[H].[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 388.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Zoledronate disodium hydrate is a bisphosphonate compound that inhibits osteoclast-mediated bone resorption and is widely used in bone metabolism and cancer research. It is highly water-soluble, forms metal ion complexes, and exhibits stability under normal conditions but requires moisture protection. Common applications include studying bone diseases, tumor-induced bone loss, and anti-inflammatory mechanisms.