MedKoo Cat#: 463242 | Name: BI4464
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BI4464 is a FAK inhibitor.

Chemical Structure

BI4464
BI4464
CAS#1227948-02-8 (free base)

Theoretical Analysis

MedKoo Cat#: 463242

Name: BI4464

CAS#: 1227948-02-8 (free base)

Chemical Formula: C28H28F3N5O4

Exact Mass: 555.2093

Molecular Weight: 555.56

Elemental Analysis: C, 60.54; H, 5.08; F, 10.26; N, 12.61; O, 11.52

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
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Synonym
BI4464; BI 4464; BI-4464;
IUPAC/Chemical Name
3-methoxy-N-(1-methylpiperidin-4-yl)-4-((4-((3-oxo-2,3-dihydro-1H-inden-4-yl)oxy)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide
InChi Key
QUSSZSMDFABHLI-UHFFFAOYSA-N
InChi Code
InChI=1S/C28H28F3N5O4/c1-36-12-10-18(11-13-36)33-25(38)17-6-8-20(23(14-17)39-2)34-27-32-15-19(28(29,30)31)26(35-27)40-22-5-3-4-16-7-9-21(37)24(16)22/h3-6,8,14-15,18H,7,9-13H2,1-2H3,(H,33,38)(H,32,34,35)
SMILES Code
O=C1CCC2=C1C(OC3=NC(NC4=C(OC)C=C(C=C4)C(NC5CCN(C)CC5)=O)=NC=C3C(F)(F)F)=CC=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 555.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL