Sulfaclozine is a sulfonamide antibiotic with antiprotozoal activity. Dietary administration of sulfaclozine reduces cecal lesion score and oocyst production in a chick model of E. tenella infection in a dose-dependent manner. It increases average survival time in a mouse model of T. gondii infection when administered at a dose of 250 mg/kg per day. Sulfaclozine has been found in chicken muscle samples from domestic markets and as an environmental contaminent in fish pond water, biogas digester water, and lagoon wastewater from pig farms. Formulations containing sulfaclozine have been used in the treatment of coccidiosis in poultry.
MedKoo Cat#: 463225
Name: Sulfaclozine sodium
CAS#: 23307-72-4 (sodium)
Chemical Formula: C10H8ClN4NaO2S
Exact Mass: 0.0000
Molecular Weight: 306.70
Elemental Analysis: C, 39.16; H, 2.63; Cl, 11.56; N, 18.27; Na, 7.50; O, 10.43; S, 10.45
The following data is based on the product molecular weight 306.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
