MedKoo Cat#: 574935 | Name: Windorphen
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Windorphen is a cell-permeable bis(4-methoxyphenyl)chloroacrylaldehyde whose (Z)-isomer (isomeric content 12-15%) acts as a p300-selective histone acetytransferase (HAT) inhibitor.

Chemical Structure

Windorphen
Windorphen
CAS#19881-70-0

Theoretical Analysis

MedKoo Cat#: 574935

Name: Windorphen

CAS#: 19881-70-0

Chemical Formula: C17H15ClO3

Exact Mass: 302.0710

Molecular Weight: 302.75

Elemental Analysis: C, 67.44; H, 4.99; Cl, 11.71; O, 15.85

Price and Availability

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25mg USD 370.00 2 Weeks
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Related CAS #
No Data
Synonym
Histone Acetyltransferase Inhibitor XII; Windorphen; WD, HAT Inhibitor XII, Wnt Pathway Inhibitor XXII
IUPAC/Chemical Name
( E) & ( Z)-3-Chloro-2,3- bis(4-methoxyphenyl)acrylaldehyde
InChi Key
VNRALGZMXHFBPG-MSUUIHNZSA-N
InChi Code
InChI=1S/C17H15ClO3/c1-20-14-7-3-12(4-8-14)16(11-19)17(18)13-5-9-15(21-2)10-6-13/h3-11H,1-2H3/b17-16-
SMILES Code
O=C/C(C1=CC=C(OC)C=C1)=C(Cl)\C2=CC=C(OC)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 302.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Hao J, Ao A, Zhou L, Murphy CK, Frist AY, Keel JJ, Thorne CA, Kim K, Lee E, Hong CC. Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen. Cell Rep. 2013 Sep 12;4(5):898-904. doi: 10.1016/j.celrep.2013.07.047. Epub 2013 Sep 5. PMID: 24012757; PMCID: PMC3923627.