UBP-296 is a selective and potent antagonist of the kainate subtype of ionotropic glutamate receptors, specifically targeting GluK1. It inhibits receptor activity by blocking glutamate binding, which has potential therapeutic applications in neurological disorders involving excitotoxicity. UBP-296 demonstrates an IC50 of approximately 43 nM for GluK1.
MedKoo Cat#: 574929
Name: UBP-296
CAS#: 745055-86-1
Chemical Formula: C15H15N3O6
Exact Mass: 333.0961
Molecular Weight: 333.30
Elemental Analysis: C, 54.05; H, 4.54; N, 12.61; O, 28.80
The following data is based on the product molecular weight 333.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
