RG-50875, also known as AG-82 and Tyrphostin 25, is an EGFR inhibitor. AG82 targets the epidermal growth factor receptor (EGFR). It inhibits EGFR autophosphorylation, thereby blocking downstream signaling pathways involved in cell proliferation and survival. AG82 has been studied for its potential anti-cancer effects, particularly in tumors driven by EGFR overactivation.
MedKoo Cat#: 574925
Name: AG82
CAS#: 118409-58-8
Chemical Formula: C10H6N2O3
Exact Mass: 202.0378
Molecular Weight: 202.17
Elemental Analysis: C, 59.41; H, 2.99; N, 13.86; O, 23.74
The following data is based on the product molecular weight 202.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
