IL-4 inhibitor is an inhibitor of IL-4. It binds to IL-4 with a Kd value of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay. It is selective for IL-4 over IL-13. IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes, indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway.
MedKoo Cat#: 463174
Name: IL-4 Inhibitor
CAS#: 1332184-63-0
Chemical Formula: C18H12FN3O2
Exact Mass: 321.0914
Molecular Weight: 321.31
Elemental Analysis: C, 67.29; H, 3.76; F, 5.91; N, 13.08; O, 9.96
The following data is based on the product molecular weight 321.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
