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MedKoo Cat#: 412152 | Name: Orphenadrine (free base)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Orphenadrine (free base) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

Chemical Structure

Orphenadrine (free base)
Orphenadrine (free base)
CAS#83-98-7 (free base)

Theoretical Analysis

MedKoo Cat#: 412152

Name: Orphenadrine (free base)

CAS#: 83-98-7 (free base)

Chemical Formula: C18H23NO

Exact Mass: 269.1780

Molecular Weight: 269.39

Elemental Analysis: C, 80.26; H, 8.61; N, 5.20; O, 5.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
4682-36-4 (citrate); 341-69-5 (HCl) 83-98-7 (free base)
Synonym
Orphenadrine (free base); BS5930; BS-5930; BS 5930
IUPAC/Chemical Name
Ethanamine, N,N-dimethyl-2-((2-methylphenyl)phenylmethoxy)-
InChi Key
QVYRGXJJSLMXQH-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H23NO/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16/h4-12,18H,13-14H2,1-3H3
SMILES Code
CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 269.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Effect of Genetic Algorithm- Based Wavelength Selection as a Preprocessing Tool on Multivariate Simultaneous Determination of Paracetamol, Orphenadrine Citrate, and Caffeine in the Presence of p-Aminophenol Impurity. J AOAC Int. 2019 Jul 5. doi: 10.5740/jaoacint.18-0393. Epub ahead of print. PMID: 31277724. 11: Hamdan II, Kasabri VN, Al-Hiari YM, El-Sabawi D, Zalloum H. Pancreatic lipase inhibitory activity of selected pharmaceutical agents. Acta Pharm. 2019 Mar 1;69(1):1-16. doi: 10.2478/acph-2019-0010. PMID: 31259721. 12: Chaumont-Olive P, Rouen M, Barozzino-Consiglio G, Ben Abdeladhim A, Maddaluno J, Harrison-Marchand A. Chiral Lithium Amido Aryl Zincates: Simple and Efficient Chemo- and Enantio-Selective Aryl Transfer Reagents. Angew Chem Int Ed Engl. 2019 Mar 4;58(10):3193-3197. doi: 10.1002/anie.201813510. Epub 2019 Jan 17. PMID: 30653791. 13: Abd-Elsalam S, El-Kalla F, Ali LA, Mosaad S, Alkhalawany W, Elemary B, Badawi R, Elzeftawy A, Hanafy A, Elfert A. 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