MedKoo Cat#: 463155 | Name: MGH-CP1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MGH-CP1 is a potent and selective TEAD palmitoylation inhibitor.

Chemical Structure

MGH-CP1
MGH-CP1
CAS#896657-58-2

Theoretical Analysis

MedKoo Cat#: 463155

Name: MGH-CP1

CAS#: 896657-58-2

Chemical Formula: C20H24N4OS

Exact Mass: 368.1671

Molecular Weight: 368.50

Elemental Analysis: C, 65.19; H, 6.57; N, 15.20; O, 4.34; S, 8.70

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,750.00 2 Weeks
1g USD 4,450.00 2 Weeks
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Related CAS #
Synonym
MGH-CP1; MGHCP1; MGH CP1;
IUPAC/Chemical Name
2-((4H-1,2,4-triazol-3-yl)thio)-N-(4-((3r,5r,7r)-adamantan-1-yl)phenyl)acetamide
InChi Key
UUKXOVBCMOZQNC-XLWGHNRJSA-N
InChi Code
InChI=1S/C20H24N4OS/c25-18(11-26-19-21-12-22-24-19)23-17-3-1-16(2-4-17)20-8-13-5-14(9-20)7-15(6-13)10-20/h1-4,12-15H,5-11H2,(H,23,25)(H,21,22,24)/t13-,14+,15-,20?
SMILES Code
O=C(NC1=CC=C(C2(C[C@H]3C4)C[C@@H](C3)C[C@@H]4C2)C=C1)CSC5=NN=CN5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 368.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Sun Y, Hu L, Tao Z, Jarugumilli GK, Erb H, Singh A, Li Q, Cotton JL, Greninger P, Egan RK, Tony Ip Y, Benes CH, Che J, Mao J, Wu X. Pharmacological blockade of TEAD-YAP reveals its therapeutic limitation in cancer cells. Nat Commun. 2022 Nov 8;13(1):6744. doi: 10.1038/s41467-022-34559-0. PMID: 36347861; PMCID: PMC9643419.