Synonym
Dimoxamine hydrochloride; Dimoxamine HCl; BL-3912A; BL3912A; BL 3912A; MDPA1; MDPA 1; MDPA-1; ariadne; 4C-D; 4C-DOM; α-Et-2C-D; BL-3912; BL 3912; BL3912;
IUPAC/Chemical Name
Benzeneethanamine, alpha-ethyl-2,5-dimethoxy-4-methyl-, hydrochloride, (R)
InChi Key
HQMDHDKBZGKPGS-RFVHGSKJSA-N
InChi Code
InChI=1S/C13H21NO2.ClH/c1-5-11(14)7-10-8-12(15-3)9(2)6-13(10)16-4;/h6,8,11H,5,7,14H2,1-4H3;1H/t11-;/m1./s1
SMILES Code
N[C@H](CC)CC1=CC(OC)=C(C)C=C1OC.[H]Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
259.77
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Glennon RA. MDMA-like stimulus effects of alpha-ethyltryptamine and the alpha-ethyl homolog of DOM. Pharmacol Biochem Behav. 1993 Oct;46(2):459-62. doi: 10.1016/0091-3057(93)90379-8. PMID: 7903460.
2: Winter JC. Effects of the phenethylamine derivatives, BL-3912, fenfluramine, and Sch-12679, in rats trained with LSD as a discriminative stimulus. Psychopharmacology (Berl). 1980;68(2):159-62. doi: 10.1007/BF00432134. PMID: 6776559.
3: Tilson HA, Chamberlain JH, Gylys JA. Further studies on BL-3912A: effects on avoidance behavior of rats with low baselines and on reaction thresholds to electric footshock. Pharmacol Biochem Behav. 1977 Jun;6(6):627-30. doi: 10.1016/0091-3057(77)90086-7. PMID: 263545.
4: Standridge RT, Howell HG, Gylys JA, Partyka RA, Shulgin AT. Phenylakylamines with potential psychotherapeutic utility. 1. 2-Amino-1-(2,5-dimethoxy-4-methylphenyl)butane. J Med Chem. 1976 Dec;19(12):1400-4. doi: 10.1021/jm00234a010. PMID: 1003425.
5: Dyer DC. Comparison of the effects of R-(-)-2-amino-1-(2,5-dimethoxy-4-methylphenyl) propane (DOM), r-(-)-2-amino-1-(2,5-dimethoxy-4-methylphenyl) butane (BL-3912A) and 5-hydroxytryptamine on non-innervated vascular smooth muscle. Res Commun Chem Pathol Pharmacol. 1976 Jul;14(3):449-54. PMID: 959651.
6: Buyniski JP, Smith ML, Bierwagen ME. Cardiovascular and gross behavioral effects of amphetamine, 2-amino-1-(2,5-dimethoxy-4-methylphenyl) propane (DOM) and 2-amino-1-(2,5-dimethoxy-4-methylphenyl) butane (BL-3912A) in the conscious dog. Res Commun Chem Pathol Pharmacol. 1974 Jun;8(2):213-21. PMID: 4859236.
7: Coppola RJ. An evaluation of 1-(4-methyl) 2, 5-dimethoxyphenyl-2-aminobutane (MDPA-1) as an enhancer of memory and learning. J Am Osteopath Assoc. 1974 Jan;73(5):406-11. PMID: 4209256.
