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MedKoo Cat#: 412112 | Name: Calcium DTPA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Calcium DTPA is an edetate and a chelating agent used in preparing radiopharmaceuticals.

Chemical Structure

Calcium DTPA
Calcium DTPA
CAS#2531-75-1 (calcium)

Theoretical Analysis

MedKoo Cat#: 412112

Name: Calcium DTPA

CAS#: 2531-75-1 (calcium)

Chemical Formula: C28H44CaN6O20

Exact Mass: 824.2236

Molecular Weight: 824.76

Elemental Analysis: C, 40.78; H, 5.38; Ca, 4.86; N, 10.19; O, 38.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
2531-75-1 (calcium) 67-43-6 (free acid)
Synonym
Calcium DTPA; Ca-DTPA; CaDTPA; Ca DTPA
IUPAC/Chemical Name
Glycine, N,N-bis(2-(bis(carboxymethyl)amino)ethyl)-, calcium salt
InChi Key
NFOCHJTZOXNSIS-UHFFFAOYSA-L
InChi Code
InChI=1S/2C14H23N3O10.Ca/c2*18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;/h2*1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);/q;;+2/p-2
SMILES Code
O=C([O-])CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O.O=C([O-])CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O.[Ca+2]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Pentetic acid (DTPA) has strong affinity for iron but also shows affinities for other heavy metals, thereby is used in the treatment of iron-storage disease and poisoning from heavy and radioactive metals. DTPA may chelate metallic moieties of unbound, extracellular radioimmunotherapeutics, thereby aggregating radioimmunotherapeutics locally to higher concentrations, and improving tumor cell radiocytotoxicity, while sparing normal tissues from the radiocytotoxic effects. In addition, DTPA is used in radioimaing procedures when complexes with radioisotopes, ex., Tc 99m or In 111.
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 100.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 824.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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