IUPAC/Chemical Name
Glycine, N-((1,1-dimethylethoxy)carbonyl)-
InChi Key
VRPJIFMKZZEXLR-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)
SMILES Code
O=C(O)CNC(OC(C)(C)C)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
175.18
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Kumar D, Vemula SR, Balasubramanian N, Cook GR. Indium-Mediated Stereoselective Allylation. Acc Chem Res. 2016;49(10):2169-2178. doi: 10.1021/acs.accounts.6b00362. Epub 2016 Oct 4. PMID: 27700084.
2: Marzo-Mas A, Conesa-Milián L, Noppen S, Liekens S, Falomir E, Murga J, Carda M, Marco JA. N-alpha-Aminoacyl Colchicines as Promising Anticancer Agents. Med Chem. 2019 Dec 2. doi: 10.2174/1573406415666191203112406. Epub ahead of print. PMID: 31793423.
3: Dutta T, Agashe HB, Garg M, Balakrishnan P, Kabra M, Jain NK. Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro. J Drug Target. 2007 Jan;15(1):89-98. doi: 10.1080/10611860600965914. Erratum in: J Drug Target. 2007 Dec;15(10):721-2. Balasubramanium, Prahlad [corrected to Balakrishnan, Prahlad]. PMID: 17365278.
4: Zink M, Hotzel K, Schubert US, Heinze T, Fischer D. Amino Acid-Substituted Dextran-Based Non-Viral Vectors for Gene Delivery. Macromol Biosci. 2019 Aug;19(8):e1900085. doi: 10.1002/mabi.201900085. Epub 2019 Jun 26. PMID: 31241856.
5: Varga L, Sasvári M, Penke B, Baláspiri O, Varró V. Metabolism of C-terminal pentapeptide of gastrin in the rat. Part IV. Catabolic pathways of the N-terminal BOC-14C-glycine fragment. Hepatogastroenterology. 1980 Apr;27(2):146-9. PMID: 7216128.
6: Lambert DM, Poupaert JH, Maloteaux JM, Dumont P. Anticonvulsant activities of N-benzyloxycarbonylglycine after parenteral administration. Neuroreport. 1994 Mar 21;5(7):777-80. doi: 10.1097/00001756-199403000-00010. PMID: 8018849.
7: Di Marco L, Hans M, Delaude L, Monbaliu JC. Continuous-Flow N-Heterocyclic Carbene Generation and Organocatalysis. Chemistry. 2016 Mar 18;22(13):4508-14. doi: 10.1002/chem.201505135. Epub 2016 Feb 16. PMID: 26880372.
8: Sun H, Gao C. Facile synthesis of multiamino vinyl poly(amino acid)s for promising bioapplications. Biomacromolecules. 2010 Dec 13;11(12):3609-16. doi: 10.1021/bm101060m. Epub 2010 Nov 29. PMID: 21114313.
9: Snider BB, Song F, Foxman BM. Total syntheses of (+/-)-anchinopeptolide D and (+/-)-cycloanchinopeptolide D. J Org Chem. 2000 Feb 11;65(3):793-800. doi: 10.1021/jo991454l. PMID: 10814012.
10: Salama EE. Synthesis of new 2-amino-1,3,4-oxadiazole derivatives with anti-salmonella typhi activity evaluation. BMC Chem. 2020 Apr 20;14(1):30. doi: 10.1186/s13065-020-00682-6. PMID: 32337509; PMCID: PMC7171753.
