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MedKoo Cat#: 461964 | Name: Sdpflrfamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sdpflrfamide is a neuropeptide. It is encoded by an exon 3' to Phe-Met-Arg-Phe-NH2 in the snail Lymnaea stagnalis.

Chemical Structure

Sdpflrfamide
Sdpflrfamide
CAS#110325-86-5

Theoretical Analysis

MedKoo Cat#: 461964

Name: Sdpflrfamide

CAS#: 110325-86-5

Chemical Formula: C42H61N11O10

Exact Mass: 879.4603

Molecular Weight: 880.02

Elemental Analysis: C, 57.32; H, 6.99; N, 17.51; O, 18.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Sdpflrfamide; Ser-As-pro-phe-leu-arg-phe-amide; Seryl-aspartyl-prolyl-phenylalanyl-leucyl-arginyl-phenylalanyl-amide
IUPAC/Chemical Name
L-Phenylalaninamide, L-seryl-L-alpha-aspartyl-L-prolyl-L-phenylalanyl-L-leucyl-L-arginyl-
InChi Key
ACTMUKLKAJMUEA-MRNVWEPHSA-N
InChi Code
InChI=1S/C42H61N11O10/c1-24(2)19-30(38(60)48-28(15-9-17-47-42(45)46)37(59)49-29(35(44)57)20-25-11-5-3-6-12-25)50-39(61)31(21-26-13-7-4-8-14-26)51-40(62)33-16-10-18-53(33)41(63)32(22-34(55)56)52-36(58)27(43)23-54/h3-8,11-14,24,27-33,54H,9-10,15-23,43H2,1-2H3,(H2,44,57)(H,48,60)(H,49,59)(H,50,61)(H,51,62)(H,52,58)(H,55,56)(H4,45,46,47)/t27-,28-,29-,30-,31-,32-,33-/m0/s1
SMILES Code
ACTMUKLKAJMUEA-MRNVWEPHSA-N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 880.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Moulis A. RFamide neuropeptide actions on the molluscan heart. Acta Biol Hung. 2004;55(1-4):335-41. PubMed PMID: 15270250. 2: Worster BM, Yeoman MS, Benjamin PR. Matrix-assisted laser desorption/ionization time of flight mass spectrometric analysis of the pattern of peptide expression in single neurons resulting from alternative mRNA splicing of the FMRFamide gene. Eur J Neurosci. 1998 Nov;10(11):3498-507. PubMed PMID:9824463. 3: Kaiser L, Geary TG, Williams JF. Dirofilaria immitis and Brugia pahangi: filarial parasites make nitric oxide. Exp Parasitol. 1998 Sep;90(1):131-4. PubMed PMID: 9709039. 4: Nesic OB, Magoski NS, McKenney KK, Syed NI, Lukowiak K, Bulloch AG. Glutamate as a putative neurotransmitter in the mollusc, Lymnaea stagnalis. Neuroscience. 1996 Dec;75(4):1255-69. PubMed PMID: 8938758. 5: Santama N, Li KW, Geraerts WP, Benjamin PR, Burke JF. Post-translational processing of the alternative neuropeptide precursor encoded by the FMRFamide gene in the pulmonate snail Lymnaea stagnalis. Eur J Neurosci. 1996 May;8(5):968-77. PubMed PMID: 8743745. 6: Kellett E, Saunders SE, Li KW, Staddon JW, Benjamin PR, Burke JF. Genomic organization of the FMRFamide gene in Lymnaea: multiple exons encoding novel neuropeptides. J Neurosci. 1994 Nov;14(11 Pt 1):6564-70. PubMed PMID: 7965060; PubMed Central PMCID: PMC6577258. 7: Macdonald M, Lutz EM, Lesser W, Cottrell GA, Sommerville J. Expression of mRNA encoding FMRFamide-related peptides (FaRPs) in the nervous system of Helix aspersa. Mol Cell Neurosci. 1994 Feb;5(1):23-34. PubMed PMID: 7980835. 8: Bright K, Kellett E, Saunders SE, Brierley M, Burke JF, Benjamin PR. Mutually exclusive expression of alternatively spliced FMRFamide transcripts in identified neuronal systems of the snail Lymnaea. J Neurosci. 1993 Jun;13(6):2719-29. PubMed PMID: 8501534; PubMed Central PMCID: PMC6576478. 9: Skingsley DR, Bright K, Santama N, van Minnen J, Brierley MJ, Burke JF, Benjamin PR. A molecularly defined cardiorespiratory interneuron expressing SDPFLRFamide/GDPFLRFamide in the snail Lymnaea: monosynaptic connections and pharmacology. J Neurophysiol. 1993 Mar;69(3):915-27. PubMed PMID: 8096540. 10: Cottrell GA, Lin JW, Llinas R, Price DA, Sugimori M, Stanley EF. FMRFamide-related peptides potentiate transmission at the squid giant synapse.Exp Physiol. 1992 Nov;77(6):881-9. PubMed PMID: 1362646. 11: Hoek RM, Li KW, van Minnen J, Geraerts WP. Chemical characterization of a novel peptide from the neuroendocrine light yellow cells of Lymnaea stagnalis. Brain Res Mol Brain Res. 1992 Nov;16(1-2):71-4. PubMed PMID: 1334202. 12: Saunders SE, Kellett E, Bright K, Benjamin PR, Burke JF. Cell-specific alternative RNA splicing of an FMRFamide gene transcript in the brain. J Neurosci. 1992 Mar;12(3):1033-9. PubMed PMID: 1347559; PubMed Central PMCID: PMC6576061. 13: Saunders SE, Bright K, Kellett E, Benjamin PR, Burke JF. Neuropeptides Gly-Asp-Pro-Phe-Leu-Arg-Phe-amide (GDPFLRFamide) and Ser-Asp-Pro-Phe-Leu-Arg-Phe-amide (SDPFLRFamide) are encoded by an exon 3' to Phe-Met-Arg-Phe-NH2 (FMRFamide) in the snail Lymnaea stagnalis. J Neurosci. 1991 Mar;11(3):740-5. PubMed PMID: 2002360; PubMed Central PMCID: PMC6575343. 14: Price DA, Lesser W, Lee TD, Doble KE, Greenberg MJ. Seven FMRFamide-related and two SCP-related cardioactive peptides from Helix. J Exp Biol. 1990 Nov;154:421-37. PubMed PMID: 1980513. 15: Buckett KJ, Dockray GJ, Osborne NN, Benjamin PR. Pharmacology of the myogenic heart of the pond snail Lymnaea stagnalis. J Neurophysiol. 1990 Jun;63(6):1413-25. PubMed PMID: 1694238. 16: Krajniak KG, Greenberg MJ, Price DA, Doble KE, Lee TD. The identification, localization, and pharmacology of FMRFamide-related peptides and SCPB in the penis and crop of the terrestrial slug, Limax maximus. Comp Biochem Physiol C. 1989;94(2):485-92. PubMed PMID: 2576783. 17: Ebberink RH, Price DA, van Loenhout H, Doble KE, Riehm JP, Geraerts WP, Greenberg MJ. The brain of Lymnaea contains a family of FMRFamide-like peptides. Peptides. 1987 May-Jun;8(3):515-22. PubMed PMID: 3658814.

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