MedKoo Cat#: 574814 | Name: Nitrodenafil
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nitrodenafil is a related compound of Sildenafil -- a phosphodiesterase inhibitor.

Chemical Structure

Nitrodenafil
CAS#147676-99-1

Theoretical Analysis

MedKoo Cat#: 574814

Name: Nitrodenafil

CAS#: 147676-99-1

Chemical Formula: C17H19N5O4

Exact Mass: 357.1437

Molecular Weight: 357.37

Elemental Analysis: C, 57.14; H, 5.36; N, 19.60; O, 17.91

Price and Availability

Size Price Availability Quantity
500mg USD 375.00 2 Weeks
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Related CAS #
No Data
Synonym
Nitrodenafil
IUPAC/Chemical Name
5-(2-Ethoxy-5-nitrophenyl)-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one
InChi Key
JMINGHHRIRWKPP-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H19N5O4/c1-4-6-12-14-15(21(3)20-12)17(23)19-16(18-14)11-9-10(22(24)25)7-8-13(11)26-5-2/h7-9H,4-6H2,1-3H3,(H,18,19,23)
SMILES Code
O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC([N+]([O-])=O)=CC=C3OCC)N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Nitrodenafil is a related compound of Sildenafil -- a phosphodiesterase inhibitor.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 357.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1. Dhariwal AK, Bavdekar SB. Sildenafil in pediatric pulmonary arterial hypertension. J Postgrad Med. 2015 Jul-Sep;61(3):181-92. doi: 10.4103/0022-3859.159421. PMID: 26119438; PMCID: PMC4943407.