MS-049 oxalate salt | CAS# 1883548-97-7 | PRMT 4 and PRMT6 inhibitor

MedKoo Cat#: 574802 | Name: MS-049 oxalate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MS-049 oxalate salt is a potent and selective inhibitor of protein arginine methyltransferases (PRMTs) PRMT 4 and PRMT6.

Chemical Structure

MS-049 oxalate

CAS#1883548-97-7 (oxalate)

Theoretical Analysis

MedKoo Cat#: 574802

Name: MS-049 oxalate

CAS#: 1883548-97-7 (oxalate)

Chemical Formula: C17H26N2O5

Exact Mass: 0.0000

Molecular Weight: 338.40

Elemental Analysis: C, 60.34; H, 7.74; N, 8.28; O, 23.64

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

1883548-97-7 (oxalate) 1502816-23-0 (free base)

Synonym

MS-049 oxalate salt; MS049 oxalate salt; MS 049 oxalate salt

IUPAC/Chemical Name

2-(4-(benzyloxy)piperidin-1-yl)-N-methylethan-1-amine oxalate

InChi Key

RWKUVRQLFRJTTR-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H24N2O.C2H2O4/c1-16-9-12-17-10-7-15(8-11-17)18-13-14-5-3-2-4-6-14;3-1(4)2(5)6/h2-6,15-16H,7-13H2,1H3;(H,3,4)(H,5,6)

SMILES Code

CNCCN(CC1)CCC1OCC2=CC=CC=C2.OC(C(O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 338.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Shen Y, Szewczyk MM, Eram MS, Smil D, Kaniskan HÜ, de Freitas RF, Senisterra G, Li F, Schapira M, Brown PJ, Arrowsmith CH, Barsyte-Lovejoy D, Liu J, Vedadi M, Jin J. Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6. J Med Chem. 2016 Oct 13;59(19):9124-9139. doi: 10.1021/acs.jmedchem.6b01033. Epub 2016 Sep 15. PMID: 27584694; PMCID: PMC5063716.