MedKoo Cat#: 574800 | Name: MRS-1845
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MRS-1845 is a store-operated calcium (SOC) channel inhibitor.

Chemical Structure

MRS-1845
MRS-1845
CAS#544478-19-5

Theoretical Analysis

MedKoo Cat#: 574800

Name: MRS-1845

CAS#: 544478-19-5

Chemical Formula: C21H22N2O6

Exact Mass: 398.1478

Molecular Weight: 398.41

Elemental Analysis: C, 63.31; H, 5.57; N, 7.03; O, 24.09

Price and Availability

Size Price Availability Quantity
5mg USD 385.00 2 Weeks
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Related CAS #
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Synonym
MRS 1845; MRS1845; MRS-1845; N-Propargylnitrendipene
IUPAC/Chemical Name
3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1-(prop-2-yn-1-yl)-1,4-dihydropyridine-3,5-dicarboxylate
InChi Key
BITHABUTZRAUGT-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H22N2O6/c1-6-11-22-13(3)17(20(24)28-5)19(18(14(22)4)21(25)29-7-2)15-9-8-10-16(12-15)23(26)27/h1,8-10,12,19H,7,11H2,2-5H3
SMILES Code
O=C(OC)C1=C(C)N(CC#C)C(C)=C(C(OCC)=O)C1C2=CC=CC([N+]([O-])=O)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 398.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Salker MS, Singh Y, Durairaj RRP, Yan J, Alauddin M, Zeng N, Steel JH, Zhang S, Nautiyal J, Webster Z, Brucker SY, Wallwiener D, Anne Croy B, Brosens JJ, Lang F. LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca2+ entry. J Mol Med (Berl). 2018 Feb;96(2):173-182. doi: 10.1007/s00109-017-1610-9. Epub 2017 Dec 11. PMID: 29230527; PMCID: PMC5778154.