KC-12291 hydrochloride is an atypical voltage-gated sodium channel blocker that inhibits sustained sodium currents (INaL) and prevents diastolic contracture in isolated atria in vitro. KC-12291 HCl displays anti-ischemic, bradycardic and cardioprotective activity in vivo.
MedKoo Cat#: 574762
Name: KC-12291 hydrochloride
CAS#: 181936-98-1
Chemical Formula: C22H28ClN3O3S
Exact Mass: 449.1540
Molecular Weight: 449.99
Elemental Analysis: C, 58.72; H, 6.27; Cl, 7.88; N, 9.34; O, 10.67; S, 7.12
The following data is based on the product molecular weight 449.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
