(-)-Donepezil | CAS# 142057-80-5 | Isomer

MedKoo Cat#: 574676 | Name: (-)-Donepezil

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(-)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.

Chemical Structure

(-)-Donepezil

CAS#142057-80-5 (S-isomer)

Theoretical Analysis

MedKoo Cat#: 574676

Name: (-)-Donepezil

CAS#: 142057-80-5 (S-isomer)

Chemical Formula: C24H29NO3

Exact Mass: 379.2147

Molecular Weight: 379.50

Elemental Analysis: C, 75.96; H, 7.70; N, 3.69; O, 12.65

Price and Availability

Size	Price	Availability	Quantity
1mg	USD 385.00	2 Weeks
5mg	USD 850.00	2 Weeks

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Related CAS #

120014-06-4 (free base) 120011-70-3 (HCl) 142698-19-9 (R-isomer) 142057-80-5 (S-isomer)

Synonym

(-)-Donepezil

IUPAC/Chemical Name

(S)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-Inden-1-one

InChi Key

ADEBPBSSDYVVLD-FQEVSTJZSA-N

InChi Code

InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/t20-/m0/s1

SMILES Code

O=C1[C@@H](CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(OC)C(OC)=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 379.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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