Demecolceine is an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Demecolceine induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
MedKoo Cat#: 574653
Name: Demecolceine
CAS#: 518-11-6
Chemical Formula: C20H23NO5
Exact Mass: 357.1576
Molecular Weight: 357.41
Elemental Analysis: C, 67.21; H, 6.49; N, 3.92; O, 22.38
The following data is based on the product molecular weight 357.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
