TQB3804, also known as EGFR-IN-7, is a selective and potent EGFR kinase inhibitor. TQB3804 displayed potent enzymatic activities for EGFRd746-750/T790M/C797S, EGFRL858R/T790M/C797S, EGFRd746-750/T790M, and EGFRL858R/T790M with IC50 of 0.46, 0.13, 0.26, and 0.19 nM respectively.
MedKoo Cat#: 408113
Name: TQB3804
CAS#: 2267329-76-8
Chemical Formula: C32H41BrN9O2P
Exact Mass: 693.2304
Molecular Weight: 694.62
Elemental Analysis: C, 55.33; H, 5.95; Br, 11.50; N, 18.15; O, 4.61; P, 4.46
The following data is based on the product molecular weight 694.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
