MedKoo Cat#: 574643 | Name: CP-339818 hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP-339818 hydrochloride is a non-peptide KV1.3 channel antagonist that preferentially binds to the C-type inactivated state of the channel.

Chemical Structure

CP-339818 hydrochloride
CP-339818 hydrochloride
CAS#478341-55-8 (HCl)

Theoretical Analysis

MedKoo Cat#: 574643

Name: CP-339818 hydrochloride

CAS#: 478341-55-8 (HCl)

Chemical Formula: C21H25ClN2

Exact Mass: 0.0000

Molecular Weight: 340.89

Elemental Analysis: C, 73.99; H, 7.39; Cl, 10.40; N, 8.22

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
250mg USD 1,450.00 2 Weeks
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Synonym
CP-339818 hydrochloride, CP-339818 HCl; CP339818 HCl; CP 339818 HCl
IUPAC/Chemical Name
N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1 pentanamine hydrochloride
InChi Key
JIRISCAPZWLWCG-QPNALZDCSA-N
InChi Code
InChI=1S/C21H24N2.ClH/c1-2-3-9-15-22-20-14-16-23(17-18-10-5-4-6-11-18)21-13-8-7-12-19(20)21;/h4-8,10-14,16H,2-3,9,15,17H2,1H3;1H/b22-20+;
SMILES Code
CCCCC/N=C1C=CN(CC2=CC=CC=C2)C3=C\1C=CC=C3.[H]Cl
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 340.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sforna L, D'Adamo MC, Servettini I, Guglielmi L, Pessia M, Franciolini F, Catacuzzeno L. Expression and function of a CP339,818-sensitive K⁺ current in a subpopulation of putative nociceptive neurons from adult mouse trigeminal ganglia. J Neurophysiol. 2015 Apr 1;113(7):2653-65. doi: 10.1152/jn.00379.2014. PubMed PMID: 25652918; PubMed Central PMCID: PMC4416569. 2: Jacobson DA, Mendez F, Thompson M, Torres J, Cochet O, Philipson LH. Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses. J Physiol. 2010 Sep 15;588(Pt 18):3525-37. doi: 10.1113/jphysiol.2010.190207. PubMed PMID: 20643768; PubMed Central PMCID: PMC2988516. 3: Lee YT, Vasilyev DV, Shan QJ, Dunlop J, Mayer S, Bowlby MR. Novel pharmacological activity of loperamide and CP-339,818 on human HCN channels characterized with an automated electrophysiology assay. Eur J Pharmacol. 2008 Feb 26;581(1-2):97-104. PubMed PMID: 18162181.