URB937 is a potent and selective inhibitor of the fatty acid amide hydrolase (FAAH) enzyme, which is responsible for the degradation of anandamide, an endogenous cannabinoid. Unlike other FAAH inhibitors, URB937 has restricted brain penetration due to its inability to cross the blood-brain barrier, selectively increasing anandamide levels in peripheral tissues, with an IC50 of 3 nM for FAAH inhibition.
MedKoo Cat#: 462581
Name: URB937
CAS#: 1357160-72-5
Chemical Formula: C20H22N2O4
Exact Mass: 354.1580
Molecular Weight: 354.41
Elemental Analysis: C, 67.78; H, 6.26; N, 7.90; O, 18.06
The following data is based on the product molecular weight 354.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
