MedKoo Cat#: 574623 | Name: CFM-1571 hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CFM-1571 hydrochloride is a soluble guanylyl cyclase (sGC) activator that inhibits collagen-stimulated platelet aggregation in vitro.

Chemical Structure

CFM-1571 hydrochloride
CFM-1571 hydrochloride
CAS#1215548-30-3 (HCl)

Theoretical Analysis

MedKoo Cat#: 574623

Name: CFM-1571 hydrochloride

CAS#: 1215548-30-3 (HCl)

Chemical Formula: C23H29ClN4O3

Exact Mass: 444.1928

Molecular Weight: 444.96

Elemental Analysis: C, 62.08; H, 6.57; Cl, 7.97; N, 12.59; O, 10.79

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Synonym
CFM-1571 hydrochloride; CFM-1571 HCl; CFM1571 HCl; CFM 1571 HCl;
IUPAC/Chemical Name
1-Benzyl-3-(3-(dimethylamino)propoxy)-N-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide Hydrochloride
InChi Key
DFVHCFCSCUCAPD-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H28N4O3.ClH/c1-26(2)14-7-15-30-22-16-21(27(25-22)17-18-8-5-4-6-9-18)23(28)24-19-10-12-20(29-3)13-11-19;/h4-6,8-13,16H,7,14-15,17H2,1-3H3,(H,24,28);1H
SMILES Code
O=C(C1=CC(OCCCN(C)C)=NN1CC2=CC=CC=C2)NC3=CC=C(OC)C=C3.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 444.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Kotzki S, Roustit M, Arnaud C, et al. Anodal iontophoresis of a soluble guanylate cyclase stimulator induces a sustained increase in skin blood flow in rats. J Pharmacol Exp Ther. 2013;346(3):424-431. doi:10.1124/jpet.113.205484