JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.
MedKoo Cat#: 462572
Name: JG-98
CAS#: 1456551-16-8 (chloride)
Chemical Formula: C24H21Cl2N3OS3
Exact Mass: 533.0224
Molecular Weight: 534.53
Elemental Analysis: C, 53.93; H, 3.96; Cl, 13.26; N, 7.86; O, 2.99; S, 17.99
The following data is based on the product molecular weight 534.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
