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MedKoo Cat#: 555826 | Name: Flavacol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Flavacol is a bioactive molecules.

Chemical Structure

Flavacol
Flavacol
CAS#495-98-7

Theoretical Analysis

MedKoo Cat#: 555826

Name: Flavacol

CAS#: 495-98-7

Chemical Formula: C12H20N2O

Exact Mass: 208.1576

Molecular Weight: 208.31

Elemental Analysis: C, 69.19; H, 9.68; N, 13.45; O, 7.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
3,6-Diisobutylpyrazinol; NSC 127442; NSC127442; NSC-127442; Flavacol;
IUPAC/Chemical Name
3,6-diisobutylpyrazin-2(1H)-one
InChi Key
UYYRKEKHAYEACU-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H20N2O/c1-8(2)5-10-7-13-11(6-9(3)4)12(15)14-10/h7-9H,5-6H2,1-4H3,(H,14,15)
SMILES Code
O=C1C(CC(C)C)=NC=C(CC(C)C)N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 208.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
This message contains search results from the National Center for Biotechnology Information (NCBI) at the U.S. National Library of Medicine (NLM). Do not reply directly to this message Sent On: Tue Aug 04 16:49:39 2020 Search: flavanol Filters: Review 20 selected items PubMed Results Items 1-20 of 20 (Display the 20 citations in PubMed) 1: Decroix L, Soares DD, Meeusen R, Heyman E, Tonoli C. Cocoa Flavanol Supplementation and Exercise: A Systematic Review. Sports Med. 2018 Apr;48(4):867-892. doi: 10.1007/s40279-017-0849-1. PMID: 29299877. 2: Lin X, Zhang I, Li A, Manson JE, Sesso HD, Wang L, Liu S. Cocoa Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta- Analysis of Randomized Controlled Trials. J Nutr. 2016 Nov;146(11):2325-2333. doi: 10.3945/jn.116.237644. Epub 2016 Sep 28. PMID: 27683874; PMCID: PMC5086796. 3: Jumar A, Schmieder RE. Cocoa Flavanol Cardiovascular Effects Beyond Blood Pressure Reduction. J Clin Hypertens (Greenwich). 2016 Apr;18(4):352-8. doi: 10.1111/jch.12715. Epub 2015 Oct 30. PMID: 26514936. 4: Nehlig A. The neuroprotective effects of cocoa flavanol and its influence on cognitive performance. Br J Clin Pharmacol. 2013 Mar;75(3):716-27. doi: 10.1111/j.1365-2125.2012.04378.x. PMID: 22775434; PMCID: PMC3575938. 5: Garcia JP, Santana A, Baruqui DL, Suraci N. The Cardiovascular effects of chocolate. Rev Cardiovasc Med. 2018 Dec 30;19(4):123-127. doi: 10.31083/j.rcm.2018.04.3187. PMID: 31064163. 6: Ried K, Fakler P, Stocks NP. Effect of cocoa on blood pressure. Cochrane Database Syst Rev. 2017 Apr 25;4(4):CD008893. doi: 10.1002/14651858.CD008893.pub3. PMID: 28439881; PMCID: PMC6478304. 7: Tuenter E, Foubert K, Pieters L. Mood Components in Cocoa and Chocolate: The Mood Pyramid. Planta Med. 2018 Aug;84(12-13):839-844. doi: 10.1055/a-0588-5534. Epub 2018 Mar 14. PMID: 29539647. 8: Williamson G. The role of polyphenols in modern nutrition. Nutr Bull. 2017 Sep;42(3):226-235. doi: 10.1111/nbu.12278. Epub 2017 Aug 15. PMID: 28983192; PMCID: PMC5601283. 9: Magrone T, Russo MA, Jirillo E. Cocoa and Dark Chocolate Polyphenols: From Biology to Clinical Applications. Front Immunol. 2017 Jun 9;8:677. doi: 10.3389/fimmu.2017.00677. PMID: 28649251; PMCID: PMC5465250. 10: Mehrinfar R, Frishman WH. Flavanol-rich cocoa: a cardioprotective nutraceutical. Cardiol Rev. 2008 May-Jun;16(3):109-15. doi: 10.1097/CRD.0b013e31815d95e2. PMID: 18414181. 11: Socci V, Tempesta D, Desideri G, De Gennaro L, Ferrara M. Enhancing Human Cognition with Cocoa Flavonoids. Front Nutr. 2017 May 16;4:19. doi: 10.3389/fnut.2017.00019. PMID: 28560212; PMCID: PMC5432604. 12: Scholey A, Owen L. Effects of chocolate on cognitive function and mood: a systematic review. Nutr Rev. 2013 Oct;71(10):665-81. doi: 10.1111/nure.12065. PMID: 24117885. 13: Durazzo A, Lucarini M, Souto EB, Cicala C, Caiazzo E, Izzo AA, Novellino E, Santini A. Polyphenols: A concise overview on the chemistry, occurrence, and human health. Phytother Res. 2019 Sep;33(9):2221-2243. doi: 10.1002/ptr.6419. Epub 2019 Jul 29. PMID: 31359516. 14: Bernatoniene J, Kopustinskiene DM. The Role of Catechins in Cellular Responses to Oxidative Stress. Molecules. 2018 Apr 20;23(4):965. doi: 10.3390/molecules23040965. PMID: 29677167; PMCID: PMC6017297. 15: Sokolov AN, Pavlova MA, Klosterhalfen S, Enck P. Chocolate and the brain: neurobiological impact of cocoa flavanols on cognition and behavior. Neurosci Biobehav Rev. 2013 Dec;37(10 Pt 2):2445-53. doi: 10.1016/j.neubiorev.2013.06.013. Epub 2013 Jun 26. PMID: 23810791. 16: Jurikova T, Mlcek J, Skrovankova S, Sumczynski D, Sochor J, Hlavacova I, Snopek L, Orsavova J. Fruits of Black Chokeberry Aronia melanocarpa in the Prevention of Chronic Diseases. Molecules. 2017 Jun 7;22(6):944. doi: 10.3390/molecules22060944. PMID: 28590446; PMCID: PMC6152740. 17: Dhakad AK, Ikram M, Sharma S, Khan S, Pandey VV, Singh A. Biological, nutritional, and therapeutic significance of Moringa oleifera Lam. Phytother Res. 2019 Nov;33(11):2870-2903. doi: 10.1002/ptr.6475. Epub 2019 Aug 27. PMID: 31453658. 18: Sies H, Hollman PC, Grune T, Stahl W, Biesalski HK, Williamson G. Protection by flavanol-rich foods against vascular dysfunction and oxidative damage: 27th Hohenheim Consensus Conference. Adv Nutr. 2012 Mar 1;3(2):217-21. doi: 10.3945/an.111.001578. PMID: 22516731; PMCID: PMC3648724. 19: Jaramillo Flores ME. Cocoa Flavanols: Natural Agents with Attenuating Effects on Metabolic Syndrome Risk Factors. Nutrients. 2019 Mar 30;11(4):751. doi: 10.3390/nu11040751. PMID: 30935075; PMCID: PMC6520706. 20: Perez-Vizcaino F, Fraga CG. Research trends in flavonoids and health. Arch Biochem Biophys. 2018 May 15;646:107-112. doi: 10.1016/j.abb.2018.03.022. Epub 2018 Mar 23. PMID: 29580946.

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