MedKoo Cat#: 535193 | Name: Firazorexton
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Firazorexton, also known as TAK-994, is an orexin receptor agonist. Firazorexton is a small-molecule and orally active compound and acts as a highly selective agonist of the orexin receptor 2 (OX2) with >700-fold selectivity over the orexin receptor 1 (OX1). Firazorexton is related to danavorexton (TAK-925).

Chemical Structure

Firazorexton
Firazorexton
CAS#2274802-95-6

Theoretical Analysis

MedKoo Cat#: 535193

Name: Firazorexton

CAS#: 2274802-95-6

Chemical Formula: C22H25F3N2O4S

Exact Mass: 470.1487

Molecular Weight: 470.51

Elemental Analysis: C, 56.16; H, 5.36; F, 12.11; N, 5.95; O, 13.60; S, 6.81

Price and Availability

Size Price Availability Quantity
5mg USD 1,950.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Firazorexton; TAK-994; TAK994; TAK 994;
IUPAC/Chemical Name
N-{(2S,3S)-1-(2-hydroxy-2-methylpropanoyl)-2-[(2,3',5'-trifluoro[1,1'-biphenyl]-3-yl)methyl]pyrrolidin-3-yl}methanesulfonamide
InChi Key
VOSAWOSMGPKQEQ-OALUTQOASA-N
InChi Code
InChI=1S/C22H25F3N2O4S/c1-22(2,29)21(28)27-8-7-18(26-32(3,30)31)19(27)11-13-5-4-6-17(20(13)25)14-9-15(23)12-16(24)10-14/h4-6,9-10,12,18-19,26,29H,7-8,11H2,1-3H3/t18-,19-/m0/s1
SMILES Code
CS(=O)(N[C@@H]1[C@H](CC2=C(F)C(C3=CC(F)=CC(F)=C3)=CC=C2)N(C(C(C)(O)C)=O)CC1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 470.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL