BAI1 is an allosteric inhibitor of Bax channel activation. It binds inactive Bax at allosteric site and inhibits tBID-mediated Bax activation. It also selectively inhibits Bax-dependent apoptosis and is a potent inhibitor of Bax-mediated mitochondrial cytochrome c release.
MedKoo Cat#: 574581
Name: BAI1 hydrochloride
CAS#: 329349-20-4 (HCl)
Chemical Formula: C19H23Br2Cl2N3O
Exact Mass: 536.9585
Molecular Weight: 540.12
Elemental Analysis: C, 42.25; H, 4.29; Br, 29.59; Cl, 13.13; N, 7.78; O, 2.96
The following data is based on the product molecular weight 540.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
