MedKoo Cat#: 574563 | Name: APC-366 free base
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

APC-366 is a selective inhibitor of mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.

Chemical Structure

APC-366 free base
APC-366 free base
CAS#158921-85-8 (free base)

Theoretical Analysis

MedKoo Cat#: 574563

Name: APC-366 free base

CAS#: 158921-85-8 (free base)

Chemical Formula: C22H28N6O4

Exact Mass: 440.2172

Molecular Weight: 440.50

Elemental Analysis: C, 59.99; H, 6.41; N, 19.08; O, 14.53

Price and Availability

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5mg USD 595.00 2 Weeks
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Related CAS #
Synonym
APC 366, APC-366, APC366
IUPAC/Chemical Name
N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide
InChi Key
SKYWIMYOGAWOMB-IRXDYDNUSA-N
InChi Code
InChI=1S/C22H28N6O4/c23-19(30)17-8-4-12-28(17)21(32)16(7-3-11-26-22(24)25)27-20(31)15-10-9-13-5-1-2-6-14(13)18(15)29/h1-2,5-6,9-10,16-17,29H,3-4,7-8,11-12H2,(H2,23,30)(H,27,31)(H4,24,25,26)/t16-,17-/m0/s1
SMILES Code
O=C(N)[C@H]1N(C([C@H](CCCNC(N)=N)NC(C2=CC=C3C=CC=CC3=C2O)=O)=O)CCC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 440.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL